SPID Platform - Our Technology - PROTEINA 프로티나

Our Technology

Our Technology
SPID Platform

Single-molecule Protein Interaction Detection Platform

A novel approach to measuring the properties of proteins

Our Single-Molecule Protein-Protein Interaction Detection (SPID) platform utilizes single-molecule imaging technology
to rapidly and accurately analyze protein and protein-protein interaction (PPI) information.

SPID Technology

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Pi-View

Single-Molecule Quantification

Our Pi-View delivers high-level information extending to the single-molecule level, derived from PPI data detected on the Pi-Chip.
Our single-molecule analysis algorithm accurately converts PPI information into digital data.
The results can be flexibly utilized according to the user's objectives, including images, analytical values, and visualization data.

Core functions

1. Acquires fluorescence signals at the single molecule level using the TIRF (Total Internal Reflection Fluorescence) optical system
2. Selectively detects target PPI complexes formed by substrate proteins on the surface of the Pi-Chip.
3. Provides autofocusing and Pi-Chip full scanning functions

Pi-Chip

Our Pi-Chip revolutionizes protein interaction analysis with its high-throughput capability and
automated sample preparation process, delivering unprecedented speed of PPI analysis.

Pi-Chip’s ultra-sensitivity allows for the detection of protein-protein interactions (PPI) across a wide range of clinical samples,
making it a versatile tool for diverse research applications.
Our unique coating on the chip minimizes nonspecific protein adsorption, ensuring selective detection of target proteins and protein complexes.
Ideal for advanced proteomic studies, the Pi-Chip 40 / 384 offers unparalleled efficiency and reliability in protein analysis.

We offer tailored extraction techniques
optimized for different human body
sample types, ensuring accurate
analysis of PPI bioinformation

Leveraging our advanced surface
technology, the Pi-Chip selectively
detects and distinguishes target proteins
or PPI complexes from background
proteins, ensuring precise and accurate
analysis.

Fluorescese-labeled probes identify the
proteins or PPI complexes captured on
the Pi-Chip in step 2.

Our single-molecule technology
detects potential PPIs, unveiling novel
information unexplored by traditional
methods.

The single molecule co-immunoprecipitation technology platform

Our Pi-View delivers high-level information extending to the single-molecule level, derived from PPI data detected on the Pi-Chip. Our single-molecule analysis algorithm accurately transforms PPI information into digital data, providing results that can be flexibly utilized based on user objectives, including images, analytical values, and visualization materials.

A versatile and comprehensive solution tailored
for drug discovery, drug development and diagnostics

Drug Discovery

Measure the interactions between a target protein and
a great number of candidate compounds much faster
than other protein analysis methods offered on the market

Mode of Action (MoA)

Better understand the mode of action of the pharmaceutical
compound in question by analyzing various target proteins
and their interactions

Target engagement

Ensure that the protein you are targeting is properly
being engaged

Drug efficacy

Generate a drug efficacy prediction model utilizing the data collected by the SPID platform

Diagnostics

Measure up to 100 PPI metrics on a sample simultaneously
in less than 2 hours, rapidly tracing the PPI landscape