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Solutions

  • Solutions
  • PPI Landscape

Antibody-antigen affinity big data generation

Ability to generate 5,000 High-quality PPI Data per week

Using our SPID Platform with our next generation 384 High Throughput Pi-chip,
we can generate high-quality antibody-antigen PPI big data as well as accurately measure antibody binding affinity.
We continue to accelerate our data generation speed as we create PPI big data for an AI-based antibody drug discovery platform.

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Antibody
PPI Big Data

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    Antibody affinity measurement

    Using SPID platform to analyze binding affinity
    and build binding affinity information matched
    with sequences

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    Antibody sequence variation

    Generating new sequences by altering some protein
    sequences within the CDR regions where antibodies
    bind to antigens

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    Antibody library generation

    Creating a large-scale sequence variant antibody library

    *SPID Platform only requires small amounts
    of antibody due to high sensitivity

AI-based antibody drug discovery platform

We are developing an AI-based antibody discovery platform, backed by our rapid antibody-antigen
PPI data generation capabilities. This will revolutionize antibody drug discovery by enabling the de novo design of antibodies
with optimal binding affinity to target antigens.

Our Antibody Drug Discovery Platform will leverage a generative AI model, developed together with Seoul National University
using PROTEINA’s rapid antibody-antigen PPI data generation to revolutionize antibody drug discovery and development.
By integrating the high-throughput capabilities of our SPID technology with our in-house generated datasets, the platform will enable
the identification and optimization of therapeutic antibodies with unprecedented efficiency.
We are currently producing 5,000 high-quality data points each week and using the generated big data to train the platform.

Our commitment to advancing antibody therapeutics ensures that our platform remains at the forefront of drug discovery innovation,
driving the creation of next-generation treatments to improve patient outcomes and push the boundaries of medicine.

Antibody affinity maturation

Leverage PPI big data analytics to optimize antibody-based therapeutics

Antibody-Based
Therapeutics

Monoclonal Antibodies, Bispecific
Antibodies, ADC, etc.

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Complementarity-Determining
Region (CDR) Sequence

CDR diversity determines
Antibody-antigen affinity

Antibody optimization through binding affinity
enhancement of the CDR regions

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Use CDR sequence variants to investigate
affinity changes, measuring high-resolution binding
affinity(KD) for each CDR sequence

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Accurately measure antibody-antigen binding affinity
with the PPI Landscape solution to swiftly select final candidates

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