PROTEINA PathFinder BCL2 assay
Receive insightful information to maximize the benefits of BCL2 inhibitor therapy for best possible outcome and enhance survival.
Biomarker
BCL2-BIM PBA, BCL2 Lv, BCL2-BAX CPX
BCLXL-BIM PBA, BCLXL-BAK CPX
MCL1-BIM PBA, MCL1-BAK CPX, MCL1 Lv
* PBA = Probe Binding Assay
* CPX = Complex
* Lv = Expression level
Pi-Chip
Suppressing non-specific binding provides true-positive signal at high confidence & sensitivity
Assay Workflow
Extraction & Detection01
PROTEINA PathFinder BCL2 assay
Targeted protein complexes are isolated from the sample and blended with PROTEINA
specialized reagents. The mixture is then placed in the wells of the Pi-Chip, where
fluorescent-signaling antibodies will attach to proteins of interest.
Quantification02
Pi-ViewPROTEINA Pi-View detects each protein complex as a point
in a displayed image
Analysis03
Pi-InsightPROTEINA Pi-Insight analysis software produces a summarized
user-friendly report detailing actionable data.
PROTEINA PathFinder BCL2 assay is Research Use Only.
PROTEINA PathFinder BCL2 assay is compatible with PROTEINA Pi-View